MartaTheir structure and interactions define cellular processes and are therefore critical
to our understanding how cells work and how diseases can be cured.
Proteins are the active ingredient of life Our mission is to develop approaches to study protein structure
and interactions in cells and make them universally accessible.
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LaptopOur mission is to develop approaches to study protein structure
and interactions in cells and make them universally accessible.
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Sven&ChristianOur mission is to develop approaches to study protein structure
and interactions in cells and make them universally accessible.
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EasysprayOur mission is to develop approaches to study protein structure
and interactions in cells and make them universally accessible.
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LATEST PUBLICATIONS

LAB NEWS

A great step forward for the field: "Toward Increased Reliability, Transparency, and Accessibility in Crosslinking Mass Spectrometry". Thank you to all colleagues involved! https://doi.org/10.1016/j.str.2020.09.011

You are interested in the "Anatomy of a crosslinker" go-ahead and check out our review in Current Opinion in Chemical Biology 😊https://www.sciencedirect.com/science/article/pii/S1367593120301046 @adambelsom

Our study showed a very different arrangement in Mycoplasma pneumoniae cells.
Taken together these studies show that transcription-translation coupling occurs in distantly related bacteria but remains to be seen how structurally diverse this coupling is.
https://science.sciencemag.org/content/369/6503/554

The two studies out today have a detailed description of how NusG (and also NusA) can bridge the RNA polymerase and ribosome in E.coli. @WebsterMichael0
https://science.sciencemag.org/content/early/2020/08/19/science.abb5036
https://science.sciencemag.org/content/early/2020/08/19/science.abb5317

Exciting new studies out today on transcription translation coupling in Science from the @R_H_Ebright lab and @AlbertW_Lab. @LaurelOld at ASBMB has written about the three papers and talks about all that is yet to be discovered.
https://www.asbmb.org/asbmb-today/science/082020/new-studies-define-transcription-translation-coupl

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Funding

We gratefully acknowledge support by our funders especially the Wellcome Trust for their willingness to fund us when our vision was daring but the prospects of ever reaching our goals still far remote. We are also deeply indebted to Edinburgh for providing a very supportive research environment and many great colleagues for being the way they are. This allowed us to ultimately overcome the key challenges of our approach. We also thank the many gifted students of Biotechnology at the TU Berlin for their curiosity and interest in technology development and the TU Berlin for providing a space to tune and scale our approach.