LATEST PUBLICATIONS

LAB NEWS

[Preprint] We experimentally demonstrate reliable FDR estimation in large scale cross-linking MS studies using the target-decoy approach. Great Work @swantjelenz LudwigSinn @FJ_OReilly https://www.biorxiv.org/content/10.1101/2020.05.25.114256v1 😊

A thorough analysis of Ultraviolet Photodissociation of tryptic peptide backbones at 213 nm. @LKolbowski @adambelsom 😊https://pubs.acs.org/doi/10.1021/jasms.0c00106

We are happy to see our preprint on the architecture of coupled transcription and translation inside cells online 🥳 Combining the power of whole cell crosslinking-MS, Cryo-ET, and integrative modeling. https://www.biorxiv.org/content/10.1101/2020.02.28.970111v1

What a fruitful cooperation 🙂 First look at the atomic structure of thyroglobulin https://www2.mrc-lmb.cam.ac.uk/first-look-at-the-atomic-structure-of-thyroglobulin/

We are currently looking for feedback on the useability and functionality of the xiVIEW visualization software. If you got some time, please participate 😊 thank you! https://edinburgh.onlinesurveys.ac.uk/xiview-usability

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Funding

We gratefully acknowledge support by our funders especially the Wellcome Trust for their willingness to fund us when our vision was daring but the prospects of ever reaching our goals still far remote. We are also deeply indebted to Edinburgh for providing a very supportive research environment and many great colleagues for being the way they are. This allowed us to ultimately overcome the key challenges of our approach. We also thank the many gifted students of Biotechnology at the TU Berlin for their curiosity and interest in technology development and the TU Berlin for providing a space to tune and scale our approach.