MartaTheir structure and interactions define cellular processes and are therefore critical
to our understanding how cells work and how diseases can be cured.
Proteins are the active ingredient of life Our mission is to develop approaches to study protein structure
and interactions in cells and make them universally accessible.
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LaptopOur mission is to develop approaches to study protein structure
and interactions in cells and make them universally accessible.
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Sven&ChristianOur mission is to develop approaches to study protein structure
and interactions in cells and make them universally accessible.
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EasysprayOur mission is to develop approaches to study protein structure
and interactions in cells and make them universally accessible.
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LATEST PUBLICATIONS

LAB NEWS

Our paper in collaboration with the Mahamid lab @embl is out in Science 🥳 We describe the architecture of transcription-translation coupling in a prokaryote entirely from in-cell data. [1/8] https://science.sciencemag.org/content/369/6503/554

EMBL scientists in the Mahamid group & colleagues @TUBerlin have created a new approach to observe molecular machines at work inside cells.

By combining three methods, they produced the
highest-resolution images ever obtained of Mycoplasma pneumoniae.

https://www.embl.org/news/science/visualising-the-cells-molecular-machinery-in-action/

Fantastic collaboration with Haering, Lowe, @Beck_Laboratory and Aragon labs. @EMBL,
@MRC_LMB. The first of a few upcoming papers where we use high-density photo-crosslinking to aid interpretation of cryo-EM maps. (with @LrSinn)
https://www.nature.com/articles/s41594-020-0457-x

First complete atomic model of condensin: Jan Lowe’s group lays the foundation for an improved understanding of chromosome assembly
https://www2.mrc-lmb.cam.ac.uk/first-complete-atomic-model-of-condensin-lays-foundation-for-understanding-chromosome-compaction/
#LMBresearch

We are happy to share that with you 🥳Studying the impact of sequential digest with trypsin on the use of alternative proteases https://pubs.acs.org/doi/full/10.1021/acs.analchem.0c00478

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Funding

We gratefully acknowledge support by our funders especially the Wellcome Trust for their willingness to fund us when our vision was daring but the prospects of ever reaching our goals still far remote. We are also deeply indebted to Edinburgh for providing a very supportive research environment and many great colleagues for being the way they are. This allowed us to ultimately overcome the key challenges of our approach. We also thank the many gifted students of Biotechnology at the TU Berlin for their curiosity and interest in technology development and the TU Berlin for providing a space to tune and scale our approach.